PREBALIN 25 MG

PREBALIN 25 MG

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Product Code : 107710720201703

Short Description

Prebalin 25 mg is a medication used to manage neuropathic pain, fibromyalgia, and as adjunctive therapy for partial-onset seizures by modulating calcium channels in the central nervous system.

Name	Brand	Generic Name	Strength	PPF	Price
PREBALIN 25 MG	General Pharmaceuticals Ltd.	PREGABALIN	25 mg	Capsule	9

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Description

• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

Indications:
Prebalin 25 mg is indicated for the treatment of:

Neuropathic pain associated with diabetic peripheral neuropathy
Post-herpetic neuralgia
Fibromyalgia
Neuropathic pain associated with spinal cord injury
Adjunctive therapy for adult patients with partial-onset seizures

Pharmacology:
Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). It binds with high affinity to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system. This binding reduces the release of excitatory neurotransmitters, thereby decreasing neuronal excitability and providing relief from pain and seizures.

Dosage:

Neuropathic Pain & Post-herpetic Neuralgia:
- Initial dose: 75 mg twice daily (150 mg/day)
- Maintenance dose: 150–300 mg/day, divided into two or three doses
Fibromyalgia:
- Initial dose: 75 mg twice daily (150 mg/day)
- Maintenance dose: 300–450 mg/day, divided into two or three doses
Partial-onset Seizures:
- Initial dose: 75 mg twice daily (150 mg/day)
- Maintenance dose: 150–300 mg/day, divided into two or three doses

Administration:

Take orally with or without food.
Swallow the capsule whole with a glass of water.
Do not crush or chew the capsule.

Interaction:

Alcohol: May increase central nervous system (CNS) depressant effects.
Lorazepam: Concurrent use may enhance CNS depressant effects.
Clozapine: May increase blood levels of pregabalin.
Other CNS depressants: Concurrent use may increase the risk of CNS depression.

Contraindications:

Hypersensitivity to pregabalin or any component of the formulation.

Side Effects:
Common side effects include:

Dizziness
Somnolence
Dry mouth
Edema
Blurred vision
Weight gain
Abnormal thinking

Serious side effects may include:

Angioedema (swelling of the throat, head, and neck)
Respiratory depression
Suicidal thoughts or behavior

Pregnancy & Lactation:

Pregnancy: Category C. Use only if the potential benefit justifies the potential risk to the fetus.
Lactation: Pregabalin is excreted in breast milk. Use with caution during breastfeeding.

Therapeutic Class: