Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
Gliride 1 mg is indicated for the treatment of type 2 diabetes mellitus in adults when diet and exercise alone are insufficient to control blood glucose levels.
Pharmacology:
Gliride 1 mg contains Glimepiride, a second-generation sulfonylurea. It works by stimulating the pancreas to release insulin and increasing the sensitivity of peripheral tissues to insulin, thereby lowering blood glucose levels.
Dosage:
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Adults:
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Initial dose: 1–2 mg once daily with breakfast or the first main meal.
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Maintenance dose: 1–4 mg once daily.
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Maximum dose: 6 mg per day.
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Elderly: Start with 1 mg once daily.
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Renal impairment: 1 mg once daily; adjust dose based on blood glucose levels.
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Hepatic impairment: Use with caution; start with a lower dose.
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Administration:
Take the tablet orally with sufficient water, immediately before or during the first main meal of the day. Do not skip meals to prevent hypoglycemia.
Interaction:
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Alcohol: May potentiate the hypoglycemic effect and increase the risk of lactic acidosis.
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Other antidiabetic agents: May enhance the hypoglycemic effect.
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Beta-blockers: May mask symptoms of hypoglycemia.
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Corticosteroids: May reduce the hypoglycemic effect.
Contraindications:
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Hypersensitivity to Glimepiride or other sulfonylureas.
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Type 1 diabetes mellitus.
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Diabetic ketoacidosis.
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Severe renal or hepatic impairment.
Side Effects:
Common side effects include:
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Hypoglycemia
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Nausea
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Dizziness
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Headache
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Weight gain
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Gastrointestinal disturbances
Pregnancy & Lactation:
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Pregnancy: Category C. Use only if the potential benefit justifies the potential risk to the fetus.
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Lactation: Excreted in breast milk; use with caution.
Therapeutic Class:
Sulfonylurea antidiabetic agent
Storage Conditions:
Store in a cool, dry place below 25°C. Keep out of reach of children.
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