• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
Perigen 5 mg is indicated for the treatment of:
Schizophrenia
Acute and chronic psychosis
Mania
Severe agitation
Anxiety and related disorders
Tics and stuttering
Nausea and vomiting
Pharmacology:
Haloperidol is a butyrophenone derivative with antipsychotic properties. It blocks postsynaptic dopamine D1 and D2 receptors in the mesolimbic system, leading to a decrease in the release of hypothalamic and hypophyseal hormones. This action produces calmness and reduces aggressiveness, hallucinations, and delusions.
Dosage:
Adults:
Moderate symptoms: 0.5 mg to 3.0 mg, 2 to 3 times daily
Severe symptoms: 3.0 mg to 5.0 mg, 2 to 3 times daily
Elderly patients: 0.5 mg to 4.5 mg, 2 to 3 times daily
Chronic or resistant cases: 3.0 mg to 6.0 mg, 2 to 3 times daily
Children:
Suggested dose for behavior disorders in disturbed and schizophrenic children is 50 micrograms per kg body weight.
Administration:
Take orally with or without food.
Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
Interaction:
May interfere with anticoagulant properties of phenindione.
Antagonizes the action of epinephrine and other sympathomimetic agents.
Inhibits the metabolism of tricyclic antidepressants, increasing plasma levels and potential toxicity.
May impair the antiparkinson effects of levodopa.
Contraindications:
Comatose states and CNS depression due to alcohol or other depressant drugs.
Severe depressive states.
Previous spastic diseases.
Lesions of the basal ganglia.
Parkinson's syndrome, except in the case of dyskinesias due to levodopa treatment.
Sensitivity to haloperidol.
Side Effects:
Common side effects include:
Headache
Drowsiness
Dry mouth
Blurred vision
Nausea
Vomiting
Anorexia
Diarrhea
Hypersalivation
Serious side effects may include:
Severe extrapyramidal reactions
Hypotension
Sedation
Respiratory depression
Pregnancy & Lactation:
Pregnancy: Safety for use during pregnancy has not been established. Use only if the potential benefit justifies the potential risk to the fetus.
Lactation: Excreted in breast milk. Use with caution during breastfeeding.
Therapeutic Class:
Butyrophenone drugs
Drugs used in tremor, tics & related disorders
Storage Conditions:
Store below 30°C.
Keep away from light and out of the reach of children.