PRESART HZ 80MG

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Product Code : 107713863800702

Short Description

PRESART HZ 80 mg combines Telmisartan and Hydrochlorothiazide to effectively manage high blood pressure, reducing the risk of cardiovascular events.

Name	Brand	Generic Name	Strength	PPF	Price
PRESART HZ 80MG	General Pharmaceuticals Ltd.	TELMISARTAN+HYDROCHLOROTHIAZIDE	80mg	TABLET	15

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• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

Indications:
PRESART HZ 80 mg is indicated for:

Treatment of essential hypertension
Reduction of cardiovascular morbidity in patients with atherothrombotic cardiovascular disease (e.g., coronary artery disease, stroke)
Patients with type 2 diabetes and documented target organ damage

Pharmacology:

Telmisartan: A non-peptide angiotensin II receptor blocker (ARB) that selectively blocks the AT1 receptor, leading to vasodilation and reduced blood pressure without affecting heart rate.
Hydrochlorothiazide: A thiazide diuretic that inhibits sodium and chloride reabsorption in the distal convoluted tubules, leading to increased excretion of sodium and water, thereby reducing blood volume and blood pressure.

Dosage:

Initial Therapy: 80 mg/12.5 mg once daily; may increase to 160 mg/25 mg once daily after 2 to 4 weeks if necessary.
Add-on Therapy: For patients not adequately controlled with amlodipine (or another dihydropyridine calcium channel blocker) alone or with telmisartan (or another angiotensin receptor blocker) alone.
Replacement Therapy: For patients receiving amlodipine and telmisartan from separate tablets, PRESART HZ 80 mg can replace the individual components.

Administration:
Take one tablet orally once daily, with or without food, at the same time each day.

Interaction:

Telmisartan: May interact with drugs like antacids, rifampicin, and certain statins, which can affect its absorption and increase side effects.
Hydrochlorothiazide: May interact with beta-blockers, ACE inhibitors, and other antihypertensive agents. Monitor blood pressure regularly.

Contraindications:

Hypersensitivity to telmisartan, hydrochlorothiazide, or any component of the formulation
Pregnancy and lactation
Severe hepatic impairment
Cardiogenic shock or left ventricular outflow tract obstruction

Side Effects:

Pregnancy & Lactation:

Pregnancy: Contraindicated, especially in the second and third trimesters due to potential fetal harm.
Lactation: Not known if excreted in human milk; consult a healthcare provider before use.

Therapeutic Class:
Combined antihypertensive preparations

Storage Conditions:
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.