Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
GENOLEV 0.5% Eye Drop is indicated for the treatment of bacterial conjunctivitis caused by susceptible strains of the following bacteria:
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Aerobic Gram-Positive bacteria:
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Corynebacterium species
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Staphylococcus aureus
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Staphylococcus epidermidis
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Streptococcus pneumoniae
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Streptococcus (Groups C/F)
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Streptococcus (Group G)
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Streptococcus viridans group
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Aerobic Gram-Negative bacteria:
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Acinetobacter lwoffii
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Haemophilus influenzae
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Serratia marcescens
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GENOLEV also provides a promising treatment for other ocular infections including bacterial corneal ulcer, blepharitis, hordeolum, and perioperative conditions.
Pharmacology:
GENOLEV 0.5% Eye Drop contains Levofloxacin, a synthetic, broad-spectrum, third-generation fluoroquinolone bactericidal antibiotic. It works by inhibiting bacterial topoisomerase IV and DNA gyrase enzymes, which are essential for DNA replication, transcription, repair, and recombination, thereby preventing bacterial cell division and growth.
Dosage:
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Adults and children 1 year of age and older:
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Days 1 and 2: Instill 1-2 drops in the affected eye(s) every 2 hours while awake, up to 8 times per day.
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Days 3 through 7: Instill 1-2 drops in the affected eye(s) every 4 hours while awake, up to 4 times per day.
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Children under 1 year: Safety and effectiveness have not been established.
Administration:
Before application, wash your hands thoroughly. Tilt your head back and gently pull down the lower eyelid to create a small pocket. Hold the dropper above the eye and instill the prescribed number of drops into the conjunctival sac. Close your eye and blink a few times to spread the medication evenly. Avoid touching the tip of the dropper to any surface to prevent contamination.
Interaction:
Specific drug interaction studies have not been conducted with GENOLEV 0.5% Eye Drop. However, systemic administration of some quinolones has been shown to elevate plasma concentrations of theophylline, interfere with the metabolism of caffeine, and enhance the effects of the oral anticoagulant warfarin and its derivatives.
Contraindications:
GENOLEV 0.5% Eye Drop is contraindicated in patients with a history of hypersensitivity to Levofloxacin, other quinolones, or any of the components of this medication.
Side Effects:
Common side effects (occurring in approximately 1-3% of patients) include:
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Transient blurred vision
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Fever
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Foreign body sensation
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Headache
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Transient ocular burning
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Ocular pain or discomfort
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Pharyngitis
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Photophobia
Less common side effects (occurring in less than 1% of patients) include:
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Allergic reactions
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Lid edema
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Ocular dryness
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Ocular itching
Pregnancy & Lactation:
Pregnancy Category C. Levofloxacin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Levofloxacin has not been measured in human milk. Caution should be exercised when Levofloxacin eye drops are administered to a nursing mother.
Therapeutic Class:
4-Quinolone preparations
Storage Conditions:
Store in a cool, dry place away from direct sunlight. Keep out of reach of children. Store at temperatures between 15°C and 25°C.
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