Betacor HZ 5/6.25 Tablet is primarily indicated for the treatment of hypertension (high blood pressure). The combination of Bisoprolol and Hydrochlorothiazide provides an additive effect in lowering blood pressure, making it suitable for patients whose condition is not adequately controlled with monotherapy. The typical starting dose is one tablet once daily, which may be adjusted based on individual response and tolerability. It's important to note that this medication should be used under medical supervision, as it may cause side effects such as dizziness, fatigue, and electrolyte imbalances. Regular monitoring of blood pressure and kidney function is recommended during treatment.