Methox 2.5 mg is a pharmaceutical preparation containing methotrexate, a potent antimetabolite and immunosuppressive agent. It is primarily indicated for the treatment of various neoplastic diseases, including gestational choriocarcinoma, chorioadenoma destruens, and hydatidiform mole. Methox is also used in the management of acute lymphoblastic leukemia and in combination with other chemotherapeutic agents for the treatment of advanced-stage non-Hodgkin’s lymphomas. Additionally, it is employed in the treatment of breast cancer, epidermoid cancers of the head and neck, advanced mycosis fungoides (cutaneous T-cell lymphoma), and lung cancer,