Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
P DOL 362.5 mg is indicated for the treatment of:
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Moderate to severe acute or chronic pain
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Post-operative pain
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Musculoskeletal pain
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Pain associated with injury or trauma
Pharmacology:
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Tramadol Hydrochloride: A centrally acting opioid analgesic that binds to μ-opioid receptors and inhibits the reuptake of norepinephrine and serotonin, altering pain perception.
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Paracetamol (Acetaminophen): A non-opioid analgesic and antipyretic that works by inhibiting prostaglandin synthesis in the CNS, enhancing the pain-relieving effect of tramadol.
Dosage:
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Adults and adolescents over 12 years: 1 tablet every 6 hours as needed.
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Maximum 4 doses per day.
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Do not exceed a total daily dose of 8 tablets (equivalent to 300 mg Tramadol and 2600 mg Paracetamol).
Administration:
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Administer orally with or without food
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Swallow whole with water
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Do not crush or chew
Interaction:
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May interact with MAO inhibitors, SSRIs, and tricyclic antidepressants
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Increased CNS depression with alcohol, sedatives, and other opioids
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Risk of serotonin syndrome with serotonergic drugs
Contraindications:
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Hypersensitivity to tramadol, paracetamol, or any excipients
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Acute intoxication with alcohol or CNS depressants
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Severe respiratory depression
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Patients with uncontrolled epilepsy
Side Effects:
Common:
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Nausea, vomiting, dizziness
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Constipation, drowsiness, sweating
Serious:
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Seizures
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Serotonin syndrome
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Liver damage with overdose
Pregnancy & Lactation:
Use only if clearly necessary and prescribed by a physician. Tramadol may cross the placenta and be secreted in breast milk; use is not recommended during lactation.
Precautions & Warnings:
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Risk of dependence or abuse with prolonged use
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Monitor liver function in long-term use
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Avoid alcohol and other CNS depressants during treatment
Therapeutic Class:
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Opioid Analgesic Combination
Storage Conditions:
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Store below 25°C in a dry place
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Keep away from direct light and moisture
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Keep out of reach of children
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