Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
ORBIDEX 3GM is indicated for:
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Treatment of uncomplicated urinary tract infections (UTIs) in women caused by susceptible strains of Escherichia coli and Enterococcus faecalis
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Prophylaxis of urinary tract infections before surgical procedures
Pharmacology:
Fosfomycin trometamol is a broad-spectrum bactericidal antibiotic. It inhibits bacterial cell wall synthesis by inactivating the enzyme enolpyruvyl transferase. This action prevents the formation of peptidoglycan, a key component of the bacterial cell wall, leading to cell lysis and death. It is excreted unchanged in the urine, where it reaches high concentrations effective against urinary pathogens.
Dosage:
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Adults (Female): One 3g sachet as a single oral dose
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Not recommended for children under 12 years unless directed by a physician
Administration:
Dissolve the contents of one sachet in a glass of water and drink immediately on an empty stomach, preferably before bedtime and after urination.
Interaction:
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Should not be taken with metoclopramide as it may reduce plasma concentration of Fosfomycin
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No significant interaction with food
Contraindications:
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Hypersensitivity to Fosfomycin or any of the formulation components
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Severe renal impairment (creatinine clearance <10 mL/min)
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Hemodialysis patients
Side Effects:
Common:
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Diarrhea
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Headache
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Nausea
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Vaginitis
Rare but serious:
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Allergic reactions (rash, itching, swelling, trouble breathing)
Pregnancy & Lactation:
Fosfomycin is classified as pregnancy category B. It may be used during pregnancy if clearly needed. Use during lactation is generally considered safe due to minimal excretion in breast milk.
Precautions & Warnings:
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Not suitable for complicated UTIs or pyelonephritis
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Ensure proper diagnosis before administration
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Not to be used repeatedly without medical advice
Therapeutic Class:
Urinary Tract Anti-infectives
Storage Conditions:
Store below 25°C in a dry place, protected from light. Keep out of reach of children.
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