Description
Jakloc XR 11 mg Tablet is a medication manufactured by Popular Pharmaceuticals Ltd. in Bangladesh. Its active ingredient, Tofacitinib, is a Janus kinase (JAK) inhibitor that modulates the immune system by interfering with the JAK-STAT signaling pathway. This action helps reduce inflammation and is used to treat conditions such as rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis in adults who have had an inadequate response or intolerance to methotrexate or other disease-modifying antirheumatic drugs (DMARDs). The "XR" in the name indicates that this is an extended-release formulation, allowing for once-daily dosing. The recommended dosage for rheumatoid arthritis and psoriatic arthritis is 11 mg once daily. For ulcerative colitis, the induction dose is 10 mg twice daily for at least 8 weeks, followed by a maintenance dose of 5 or 10 mg twice daily. The safety and effectiveness of Jakloc XR in pediatric patients have not been established. Common side effects may include upper respiratory tract infections, headache, diarrhea, and nasopharyngitis. It is important to use this medication under the supervision of a healthcare provider.
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