Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
BISOPRO is indicated for:
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Essential hypertension
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Chronic stable angina
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Stable chronic heart failure with reduced ejection fraction
Pharmacology:
Bisoprolol is a highly selective β1-adrenergic receptor blocker. It reduces heart rate and myocardial contractility, lowering blood pressure and oxygen demand. It also decreases renin activity.
Dosage & Administration:
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Hypertension/Angina: Start with 2.5–5 mg once daily. Maximum 10 mg/day.
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Heart failure: Start with 1.25 mg once daily, gradually increase to target dose (up to 10 mg), based on tolerance.
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Take preferably in the morning, with or without food.
Interaction:
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May potentiate the effect of other antihypertensives.
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Caution with calcium channel blockers (verapamil/diltiazem), insulin, and digitalis.
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NSAIDs may reduce its antihypertensive effect.
Contraindications:
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Hypersensitivity to Bisoprolol
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Acute heart failure
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Second or third-degree AV block
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Severe bradycardia or hypotension
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Bronchial asthma or severe COPD
Side Effects:
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Common: Fatigue, dizziness, bradycardia
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Others: Cold extremities, gastrointestinal discomfort, sleep disturbances
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Rare: Depression, hypotension, allergic reactions
Pregnancy & Lactation:
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Not recommended unless essential
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May cause fetal growth retardation or neonatal effects
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Use caution in lactation
Precautions & Warnings:
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Taper dose gradually when discontinuing
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Monitor heart rate, blood pressure regularly
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Use caution in diabetes, thyroid disorders, renal or hepatic impairment
Therapeutic Class:
Beta-1 selective (cardioselective) beta-blocker
Storage Conditions:
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
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