Osartil 100/12.5 is a combination tablet manufactured by Incepta Pharmaceuticals Ltd., containing 100 mg of losartan potassium and 12.5 mg of hydrochlorothiazide. This formulation is designed to effectively manage hypertension (high blood pressure) by utilizing the complementary mechanisms of its components.
Losartan, an angiotensin II receptor blocker (ARB), works by relaxing blood vessels, thereby lowering blood pressure and reducing the workload on the heart. Hydrochlorothiazide, a thiazide diuretic, helps reduce fluid retention by promoting the excretion of sodium and water through the kidneys, further aiding in blood pressure control. Together, these medications enhance the antihypertensive effect, making Osartil 100/12.5 suitable for patients whose blood pressure is inadequately controlled with either agent alone