Description
Osartil Plus 100 mg is a combination tablet manufactured by Incepta Pharmaceuticals Ltd., comprising 100 mg of losartan potassium and 25 mg of hydrochlorothiazide. This formulation is designed to effectively manage hypertension (high blood pressure) by utilizing the complementary mechanisms of its components.
Losartan, an angiotensin II receptor blocker (ARB), works by relaxing blood vessels, thereby lowering blood pressure and reducing the workload on the heart. Hydrochlorothiazide, a thiazide diuretic, helps reduce fluid retention by promoting the excretion of sodium and water through the kidneys, further aiding in blood pressure control. Together, these medications enhance the antihypertensive effect, making Osartil Plus 100 mg suitable for patients whose blood pressure is inadequately controlled with either agent alone.
This combination therapy is also indicated to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, a condition where the heart's left ventricle thickens due to high blood pressure. Additionally, it may be used to provide renal protection in hypertensive type 2 diabetic patients with proteinuria, helping to delay the progression of kidney disease.
Osartil Plus 100 mg is typically administered once daily, with or without food, and should be taken as directed by a healthcare professional. Common side effects may include dizziness, headache, fatigue, and electrolyte imbalances. Patients should inform their doctor of any existing medical conditions, especially kidney or liver issues, and any other medications they are taking to avoid potential interactions. Regular monitoring of blood pressure and kidney function is recommended during treatment.
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