Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
DULOXEN is indicated for:
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Major depressive disorder
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Generalized anxiety disorder
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Diabetic peripheral neuropathic pain
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Fibromyalgia and chronic musculoskeletal pain
Pharmacology:
Duloxetine inhibits the reuptake of serotonin and norepinephrine in the central nervous system, increasing their levels and improving mood, pain modulation, and anxiety symptoms.
Dosage & Administration:
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Adults: Typically start with 30 mg once daily; dose may be increased up to 60 mg daily based on clinical response.
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Can be taken with or without food.
Interaction:
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Caution with MAO inhibitors, SSRIs, SNRIs, and other serotonergic drugs due to risk of serotonin syndrome.
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Interaction with anticoagulants, alcohol, and CYP1A2 inhibitors.
Contraindications:
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Hypersensitivity to Duloxetine
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Use of MAO inhibitors within 14 days
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Uncontrolled narrow-angle glaucoma
Side Effects:
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Nausea, dry mouth, dizziness, fatigue
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Insomnia, constipation
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Rare: liver toxicity, serotonin syndrome
Pregnancy & Lactation:
Use only if clearly needed; consult doctor before use during pregnancy or breastfeeding.
Precautions & Warnings:
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Monitor for worsening depression or suicidal thoughts
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Gradual dose tapering recommended to avoid withdrawal symptoms
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Use cautiously in patients with hepatic or renal impairment
Therapeutic Class:
Serotonin-Norepinephrine Reuptake Inhibitor (SNRI)
Storage Conditions:
Store below 30°C in a dry, cool place, protected from light. Keep out of reach of children.
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