Nyclobate Scalp Application 30 ml is a potent topical corticosteroid formulation containing 0.05% Clobetasol Propionate, designed for the treatment of various inflammatory scalp conditions. Manufactured by Incepta Pharmaceuticals Ltd., this solution is indicated for managing recalcitrant corticosteroid-responsive dermatoses of the scalp, including psoriasis and seborrheic dermatitis . Clobetasol Propionate exhibits anti-inflammatory, antipruritic, and vasoconstrictive properties, working by inhibiting multiple inflammatory pathways, reducing cytokine production, and suppressing immune responses . The recommended usage involves applying the solution once or twice daily to the affected scalp areas, gently massaging it in, with a maximum weekly dose not exceeding 50 ml. Treatment should be limited to brief periods, discontinuing if no improvement is observed after one week or upon lesion resolution . Potential side effects include skin thinning, irritation, and, with prolonged use, systemic absorption leading to features of hypercortisolism . Nyclobate Scalp Application is contraindicated in individuals with scalp infections, hypersensitivity to the preparation, and is not recommended for children under one year of age . As with all corticosteroids, it should be used under medical supervision to minimize risks and ensure efficacy.MedicineBangla+6