Nyclobate 10 gm is a topical corticosteroid cream containing clobetasol propionate 0.05% w/w, manufactured by Incepta Pharmaceuticals Ltd. It is used to treat various inflammatory skin conditions, including eczema, psoriasis, and dermatitis, by reducing redness, swelling, and itching. Clobetasol propionate works by inhibiting the production of inflammatory substances in the body, thereby alleviating symptoms associated with these skin disorders. This medication is intended for short-term use and should be applied sparingly to the affected areas as directed by a healthcare professional. Common side effects may include skin irritation, burning, itching, or dryness at the application site. Prolonged use or application to large areas of skin may increase the risk of more serious side effects, such as skin thinning or hormonal imbalances. It is important to follow the prescribed usage instructions and consult a healthcare provider if symptoms persist or worsen