Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
QUIET is indicated for:
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Schizophrenia in adults and adolescents
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Bipolar disorder (mania and depression phases)
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Adjunctive therapy in major depressive disorder (MDD)
Pharmacology:
Quetiapine is an atypical antipsychotic that acts on serotonin (5-HT2) and dopamine (D2) receptors. It helps in reducing hallucinations, improving mood, and stabilizing behavior. It also has affinity for histamine and adrenergic receptors, contributing to its sedative effects.
Dosage & Administration:
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Schizophrenia/Bipolar: Initial dose usually 25 mg twice daily; gradually titrated up as needed.
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Dosage varies based on condition and patient response.
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Take with or without food; usually administered at night due to sedation.
Interaction:
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Use caution with CNS depressants (benzodiazepines, alcohol)
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May interact with CYP3A4 inhibitors (e.g., ketoconazole)
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Avoid QT-prolonging agents
Contraindications:
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Hypersensitivity to Quetiapine
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Severe hepatic impairment (adjustment needed)
Side Effects:
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Common: Drowsiness, dry mouth, dizziness, weight gain
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Others: Constipation, orthostatic hypotension, increased cholesterol
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Rare: Neuroleptic malignant syndrome, extrapyramidal symptoms
Pregnancy & Lactation:
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Use only if clearly needed and prescribed
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Not recommended during breastfeeding without physician's advice
Precautions & Warnings:
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Risk of suicidal thoughts in young adults
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Monitor for metabolic changes (glucose, lipids, weight)
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Use caution in elderly with dementia-related psychosis (increased mortality risk)
Therapeutic Class:
Atypical antipsychotics (second generation)
Storage Conditions:
Store below 30°C in a dry place, away from direct sunlight. Keep out of reach of children.
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