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Nobesit 500 mg Tablet

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Out Of Stock

Product Code : 110319643000601

Short Description

Nobesit 500 mg contains Metformin Hydrochloride, an oral antidiabetic used to manage type 2 diabetes mellitus.

Name Brand Generic Name Strength PPF Price
Nobesit 500 mg Tablet Incepta Pharmaceuticals Ltd. METFORMIN HYDROCHLORIDE 500 mg TABLET 4
৳ 4
Qty :

Description

• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।


Indications:

Nobesit 500 mg is indicated for:

  • Type 2 diabetes mellitus (non-insulin-dependent)

  • Monotherapy or in combination with other antidiabetics or insulin

  • Polycystic ovary syndrome (PCOS) – off-label use

  • Prevention of type 2 diabetes in high-risk individuals (off-label)

Pharmacology:

Metformin is a biguanide antidiabetic agent. It works by:

  • Decreasing hepatic glucose production

  • Increasing insulin sensitivity

  • Enhancing peripheral glucose uptake and utilization

  • Reducing intestinal absorption of glucose
    It does not stimulate insulin secretion, thus minimizing the risk of hypoglycemia.

Dosage:

As prescribed by a registered physician.
Typical starting dose: 500 mg once or twice daily with meals.
Maximum recommended daily dose: 2000–2500 mg (divided).

Administration:

Take with meals to reduce gastrointestinal side effects. Swallow the tablet whole with water. Do not crush or chew.

Interaction:

  • May increase risk of lactic acidosis with alcohol

  • May interact with iodine contrast agents, diuretics, corticosteroids, and beta-blockers

  • Caution when combined with insulin or sulfonylureas (risk of hypoglycemia)

Contraindications:

  • Severe renal impairment (eGFR <30 ml/min)

  • Acute or chronic metabolic acidosis

  • History of lactic acidosis

  • Hypersensitivity to Metformin

Side Effects:

  • Common: Nausea, vomiting, diarrhea, abdominal pain, loss of appetite

  • Rare: Lactic acidosis (serious but rare), metallic taste, B12 deficiency with long-term use

Pregnancy & Lactation:

Generally considered safe during pregnancy under medical supervision. Present in breast milk but generally safe during breastfeeding.

Precautions & Warnings:

  • Monitor kidney function regularly

  • Use caution in elderly patients and those with heart failure

  • Stop temporarily before iodinated contrast imaging

  • Avoid excessive alcohol consumption

Therapeutic Class:

Biguanide-type oral hypoglycemic agents

Storage Conditions:

Store below 25°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.