রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
Indications:
Cardobis Plus 5/6.25MG is indicated for the treatment of hypertension in patients requiring combination therapy to achieve better control of blood pressure.
Pharmacology:
Nebivolol (5mg): A beta-1 adrenergic receptor blocker that decreases heart rate and myocardial contractility, leading to reduced blood pressure.
Hydrochlorothiazide (6.25mg): A diuretic that increases the excretion of sodium and water, reducing blood volume and systemic vascular resistance.
Dosage and Administration:
Standard Dose: One tablet daily, preferably in the morning.
Can be taken with or without food. Swallow the tablet whole with a glass of water.
Interaction:
Concurrent use with other antihypertensives may cause excessive hypotension.
Potential interaction with NSAIDs, which may reduce the diuretic effect.
Use caution with medications that affect electrolyte balance.
Contraindications:
Known hypersensitivity to Nebivolol, Hydrochlorothiazide, or other components of the tablet.
Severe renal or hepatic dysfunction.
Patients with anuria or severe electrolyte imbalance.
Side Effects:
Common: Headache, dizziness, fatigue, mild hypotension.
Rare: Electrolyte disturbances, hyperglycemia, and bradycardia.
Pregnancy & Lactation:
Not recommended during pregnancy as it may cause harm to the fetus.
Should be avoided during breastfeeding due to potential excretion in breast milk.
Precautions & Warnings:
Monitor blood pressure and kidney function regularly.
Use with caution in patients with diabetes, gout, or a history of electrolyte imbalance.
Avoid sudden discontinuation to prevent rebound hypertension.
Therapeutic Class:
Antihypertensive agents (beta-blocker and diuretic combination).
Storage Conditions:
Store below 30°C in a dry place, away from direct light and moisture.
Keep the medicine out of reach of children.