• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
Mig 2.5mg Tablet is indicated for the acute treatment of migraine attacks with or without aura in adults.
Pharmacology:
Zolmitriptan is a selective serotonin (5-HT1B/1D) receptor agonist. It works by causing vasoconstriction of dilated cranial blood vessels and inhibiting the release of pro-inflammatory neuropeptides, thereby alleviating migraine symptoms.
Dosage:
Adults: The recommended initial dose is 2.5 mg. If the migraine persists or returns, a second dose may be taken after at least 2 hours. The maximum daily dose should not exceed 10 mg.
Administration:
Administer orally with or without food. The tablet should be swallowed whole with water.
Interaction:
Concurrent use with ergotamine-containing or ergot-type medications (e.g., dihydroergotamine, methysergide) is contraindicated.
Caution is advised when used with selective serotonin reuptake inhibitors (SSRIs) or serotonin-norepinephrine reuptake inhibitors (SNRIs) due to the risk of serotonin syndrome.
Contraindications:
Hypersensitivity to Zolmitriptan or any component of the formulation.
Ischemic heart disease, uncontrolled hypertension, or cerebrovascular syndromes.
Use within 24 hours of another 5-HT1 agonist or ergotamine-containing medication.
Side Effects:
Common: Dizziness, somnolence, asthenia, nausea.
Uncommon: Palpitations, dry mouth, chest discomfort.
Rare: Hypersensitivity reactions, including anaphylaxis.
Pregnancy & Lactation:
Zolmitriptan should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is excreted in breast milk; caution is advised when administering to nursing mothers.
Precautions & Warnings:
Not intended for prophylactic therapy of migraine or for the treatment of cluster headaches.
Evaluate patients for cardiovascular risk factors before initiating therapy.
Monitor for signs of serotonin syndrome, especially when used concomitantly with SSRIs or SNRIs.
Therapeutic Class:
Selective serotonin (5-HT1B/1D) receptor agonists (Triptans).
Storage Conditions:
Store at room temperature, below 30°C, in a cool, dry place away from light and moisture. Keep out of reach of children.