Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
Indications:
Cilny 10 MG Tablet is indicated for:
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Management of hypertension (high blood pressure)
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Prevention of angina pectoris (chest pain due to heart-related issues)
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Reducing the risk of heart attacks and strokes in hypertensive patients
Pharmacology:
Cilnidipine is a dihydropyridine calcium channel blocker that inhibits L-type and N-type calcium channels. This dual action leads to vasodilation, reducing peripheral vascular resistance and blood pressure. It also decreases sympathetic nerve activity, contributing to its antihypertensive effects.
Dosage and Administration:
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Adults: 5–10 mg once daily after breakfast. The dose may be increased up to 20 mg per day based on the patient's response and clinical condition.
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Elderly: Initiate therapy with the lowest possible dose (5 mg) due to increased susceptibility to hypotension.
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Pediatric Use: Safety and efficacy in patients under 18 years have not been established.
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Administration: Take orally with water, preferably after meals. Do not crush or chew the tablet.
Interaction:
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Antihypertensive agents: Concurrent use may enhance blood pressure-lowering effects.
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CYP3A4 inhibitors: May increase plasma concentration of Cilnidipine.
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Grapefruit juice: Avoid consumption as it can increase the absorption of Cilnidipine, leading to excessive hypotension.
Contraindications:
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Known hypersensitivity to Cilnidipine or any component of the formulation.
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Severe aortic stenosis.
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Cardiogenic shock.
Side Effects:
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Common: Headache, dizziness, flushing, palpitations, peripheral edema (especially ankle swelling), fatigue.
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Rare: Gingival hyperplasia, skin rash, gastrointestinal discomfort.
Pregnancy & Lactation:
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Pregnancy: Not recommended due to potential risk to the fetus. Use only if clearly needed and prescribed by a physician.
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Lactation: Caution is advised; consult a physician before use.
Precautions & Warnings:
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Use with caution in patients with severe hepatic or renal impairment.
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Monitor blood pressure regularly to avoid excessive hypotension.
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Abrupt discontinuation may lead to rebound hypertension; taper off under medical supervision.
Therapeutic Class:
Calcium channel blockers (Dihydropyridine class)
Storage Conditions:
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Store below 30°C in a dry place, away from direct sunlight.
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Keep out of reach of children.
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