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TIBONOR 2.5 MG

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Out Of Stock

Product Code : 123119665000301

Short Description

Tibonor 2.5 mg is a synthetic steroid hormone used in hormone replacement therapy to alleviate menopausal symptoms.

Name Brand Generic Name Strength PPF Price
TIBONOR 2.5 MG SK+F Pharmaceuticals Ltd. TIBOLONE 2.5 mg TABLET 20
৳ 20
Qty :

Description

• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

Indications:

  • Menopausal symptoms such as hot flashes, night sweats, and vaginal dryness

  • Prevention and treatment of postmenopausal osteoporosis

Pharmacology:
Tibolone is a synthetic steroid with estrogenic, progestogenic, and androgenic properties. It is metabolized into three active metabolites: 3α-hydroxytibolone and 3β-hydroxytibolone (estrogenic effects), and the Δ4-isomer (progestogenic and androgenic effects). These metabolites act on various tissues to alleviate menopausal symptoms and prevent bone loss.

Dosage & Administration:

  • Adults: 2.5 mg orally once daily

  • Administration: Swallow the tablet whole with water, at the same time each day

  • Starting Treatment: Initiate at least 12 months after the last natural menstrual period or immediately in women with surgical menopause

  • Switching from HRT: Begin tibolone the day after completing a sequential HRT regimen or at any time after a continuous-combined HRT regimen

Interaction:

  • May interact with enzyme-inducing drugs like barbiturates, carbamazepine, and rifampicin, potentially reducing tibolone's effectiveness

  • May enhance the effects of anticoagulants due to increased fibrinolytic activity

Contraindications:

  • Hypersensitivity to tibolone or any component of the tablet

  • History of breast cancer or endometrial cancer

  • Undiagnosed vaginal bleeding

  • Severe liver disease

  • History of thromboembolic disorders

Side Effects:

  • Common: Weight gain, abdominal pain, breast tenderness, headache, mood changes

  • Less common: Acne, increased hair growth, vaginal bleeding

  • Serious: Risk of stroke, breast cancer, endometrial cancer

Pregnancy & Lactation:

  • Pregnancy: Contraindicated; may harm the developing fetus

  • Lactation: Not recommended; may affect milk production and composition

Precautions & Warnings:

  • Regular monitoring is advised, including breast exams and mammography

  • Not recommended for women with a history of hormone-sensitive cancers

  • Use with caution in women with cardiovascular risk factors

Therapeutic Class:
Hormone Replacement Therapy (HRT)

Storage Conditions:
Store below 30°C in a dry place, away from light and moisture. Keep out of reach of children.