Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
📄 Long Description
Indications:
SIDOPLUS 50MG is indicated for the treatment of:
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Essential hypertension
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Chronic stable angina
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Post-myocardial infarction patients
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Refractory angina pectoris where nitrate therapy has failed
Pharmacology:
This fixed-dose combination contains:
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Amlodipine: A dihydropyridine calcium channel blocker that inhibits calcium influx into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure.
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Atenolol: A cardioselective beta-blocker that reduces heart rate, cardiac output, and blood pressure by blocking beta-1 adrenergic receptors.
The combination provides complementary mechanisms to control hypertension and angina.
Dosage:
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Adults: One tablet (Amlodipine 5mg + Atenolol 50mg) once daily. If necessary, dosage may be increased to two tablets daily or as advised by the physician.
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Elderly: Initiate with one tablet daily; adjust dosage based on clinical response.
Administration:
Take SIDOPLUS 50MG orally with or without food. It is recommended to take the medication at the same time each day to maintain consistent blood levels.
Interaction:
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Disopyramide: Atenolol may reduce the clearance of disopyramide, leading to additive negative inotropic effects.
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Ampicillin (≥1g): May reduce plasma levels of Atenolol.
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Oral antidiabetics and insulin: Beta-blockers may decrease tissue sensitivity to insulin and inhibit insulin secretion.
Contraindications:
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Hypersensitivity to Amlodipine, Atenolol, or any component of the formulation.
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Sinus bradycardia
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Second or third-degree heart block
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Cardiogenic shock
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Hypotension
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Congestive heart failure
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Poor left ventricular function
Side Effects:
Common side effects include:
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Fatigue
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Headache
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Peripheral edema
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Nausea
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Drowsiness
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Anxiety and depression
Pregnancy & Lactation:
Use during pregnancy only if the potential benefit justifies the potential risk to the fetus. The combination should not be used by nursing mothers; if necessary, breastfeeding should be discontinued.
Precautions & Warnings:
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Use with caution in patients with airway obstruction, renal impairment, or hepatic impairment.
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Monitor blood pressure regularly to avoid hypotension.
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Gradual withdrawal is recommended to prevent rebound hypertension.
Therapeutic Class:
Combined antihypertensive preparations
Storage Conditions:
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
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