UROKIT 10MG

UROKIT 10MG

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Product Code : 123119653200101

Short Description

Urocit-K 10mg Tablet contains potassium citrate 10mEq, an alkalinizing agent used to prevent kidney stones and manage renal tubular acidosis

Name	Brand	Generic Name	Strength	PPF	Price
UROKIT 10MG	SK+F Pharmaceuticals Ltd.	POTASSIUM CITRATE	10mg	TABLET	200

৳ 200

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Description

• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

Indications:

Renal tubular acidosis (RTA) with calcium stones
Hypocitraturic calcium oxalate nephrolithiasis of any etiology
Uric acid lithiasis with or without calcium stones

Pharmacology:
Urocit-K is a citrate salt of potassium. When administered orally, it is metabolized to produce an alkaline load, increasing urinary pH and citrate levels. This effect helps to prevent the formation of kidney stones by reducing urinary calcium and uric acid concentrations. The rise in urinary citrate and pH is dose-dependent and can be monitored through urinary tests.

Dosage & Administration:

Severe hypocitraturia (urinary citrate <150 mg/day): Initiate therapy at 60 mEq/day, administered as 30 mEq twice daily or 20 mEq three times daily with meals or within 30 minutes after meals or bedtime snack.
Mild to moderate hypocitraturia (urinary citrate >150 mg/day): Initiate therapy at 30 mEq/day, administered as 15 mEq twice daily or 10 mEq three times daily with meals or within 30 minutes after meals or bedtime snack.
Maximum recommended dose is 100 mEq/day.
Dosage adjustments should be based on urinary citrate levels and pH measurements.

Interaction:

Concurrent use with potassium-sparing diuretics (e.g., spironolactone, amiloride) may increase the risk of hyperkalemia.
Caution is advised when used with ACE inhibitors, angiotensin II receptor blockers, or other medications that can elevate potassium levels.
Avoid use with salt substitutes containing potassium.

Contraindications:

Hyperkalemia or conditions predisposing to hyperkalemia (e.g., chronic renal failure, uncontrolled diabetes, adrenal insufficiency)
Severe renal insufficiency (glomerular filtration rate <0.7 ml/kg/min)
Peptic ulcer disease
Active urinary tract infection
Gastrointestinal obstruction or stricture
Hypersensitivity to any component of the product

Side Effects:

Common: Nausea, vomiting, diarrhea, abdominal discomfort
Serious: Hyperkalemia (muscle weakness, irregular heartbeat, fatigue), gastrointestinal bleeding, allergic reactions (e.g., rash, swelling, difficulty breathing)
An empty tablet shell may appear in the stool; this is harmless as the medication has been absorbed.

Pregnancy & Lactation:

Pregnancy: Use only if the potential benefit justifies the potential risk to the fetus.
Lactation: It is not known whether potassium citrate is excreted in breast milk; use with caution during breastfeeding.

Precautions & Warnings:

Monitor serum potassium levels regularly during treatment.
Maintain adequate hydration and limit dietary salt intake.
Discontinue therapy if hyperkalemia, significant rise in serum creatinine, or significant fall in blood hematocrit or hemoglobin occurs.
Periodic electrocardiograms may be necessary to monitor for cardiac effects.

Therapeutic Class:
Urinary alkalinizing agents

Storage Conditions: