Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
Indications:
Dumax 60mg Tablet is indicated for:
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Major depressive disorder (MDD) treatment
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Management of generalized anxiety disorder (GAD)
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Relief from diabetic peripheral neuropathic pain
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Chronic musculoskeletal pain management
Pharmacology:
Duloxetine, the active ingredient, is a serotonin-norepinephrine reuptake inhibitor (SNRI) that enhances the activity of these neurotransmitters in the brain. This action helps in improving mood, alleviating anxiety, and interrupting pain signal transmission.
Dosage and Administration:
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Dosage:
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Depression: 60 mg once daily, adjusted based on patient response
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Anxiety or neuropathic pain: Start with 30 mg, increase to 60 mg if needed
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Administration:
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Take orally, with or without food.
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Swallow the tablet whole without crushing or chewing.
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Interaction:
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Avoid combining with monoamine oxidase inhibitors (MAOIs) to prevent serotonin syndrome.
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Increased sedation with alcohol or other CNS depressants.
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Potential interaction with anticoagulants, increasing bleeding risks.
Contraindications:
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Hypersensitivity to Duloxetine
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Concurrent MAOI use or uncontrolled hypertension
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Severe hepatic or renal impairment
Side Effects:
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Common: Nausea, fatigue, dry mouth, dizziness, or insomnia
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Rare: Hypertension, liver enzyme elevation, or serotonin syndrome
Pregnancy & Lactation:
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Pregnancy: Use only if necessary; benefits must outweigh risks.
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Lactation: May pass into breast milk; consult a healthcare provider.
Precautions & Warnings:
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Monitor for worsening depression or suicidal ideation, especially in younger patients.
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Use cautiously in patients with glaucoma, bipolar disorder, or seizure history.
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Gradual tapering is recommended when discontinuing to avoid withdrawal effects.
Therapeutic Class:
Serotonin-norepinephrine reuptake inhibitor (SNRI).
Storage Conditions:
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Store in a cool, dry place below 30°C.
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Protect from light and moisture.
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Keep out of reach of children.
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