Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
Cardizem 60 mg is indicated for the treatment of:
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Chronic stable angina
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Hypertension (high blood pressure)
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Supraventricular arrhythmias including atrial fibrillation and atrial flutter
Pharmacology:
Diltiazem is a nondihydropyridine calcium channel blocker that inhibits calcium ion influx across cardiac and vascular smooth muscle, resulting in vasodilation and decreased myocardial contractility. This reduces blood pressure and myocardial oxygen demand, and improves oxygen supply.
Dosage:
Adult dose: 60 mg 3 to 4 times daily, typically before meals and at bedtime.
Dosage should be individualized based on patient response.
Administration:
Take orally, preferably before meals. Swallow the tablet whole with water. Do not crush or chew.
Interaction:
May interact with:
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Beta-blockers (e.g., atenolol, metoprolol)
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Digoxin
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CYP3A4 inhibitors and inducers
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Statins (increased risk of myopathy)
Contraindications:
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Sick sinus syndrome (without pacemaker)
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Second or third-degree AV block
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Severe hypotension
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Acute myocardial infarction with pulmonary congestion
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Hypersensitivity to Diltiazem
Side Effects:
Common: Dizziness, headache, flushing, fatigue, edema, bradycardia
Less common: Nausea, constipation, rash, AV block, liver enzyme elevation
Pregnancy & Lactation:
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Use only if clearly needed during pregnancy.
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Diltiazem is excreted in human milk; breastfeeding is not recommended unless benefits outweigh risks.
Precautions & Warnings:
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Monitor blood pressure and heart rate regularly.
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Use cautiously in patients with hepatic or renal impairment.
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May worsen heart failure or conduction abnormalities.
Therapeutic Class:
Calcium Channel Blockers – Non-dihydropyridine group
Storage Conditions:
Store below 30°C in a cool, dry place. Protect from light and moisture. Keep out of the reach of children.
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