Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
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Gastroesophageal reflux disease (GERD)
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Gastric and duodenal ulcers
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Hypersecretory conditions like Zollinger-Ellison syndrome
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Acid indigestion and heartburn
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Pediatric reflux esophagitis
Pharmacology:
Famotidine is a potent and selective histamine H2 receptor antagonist. It inhibits the final step of acid production by blocking H2 receptors on the gastric parietal cells, thus reducing both basal and stimulated gastric acid secretion.
Dosage:
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Adults: 10–20 ml twice daily depending on severity (as prescribed)
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Children (above 1 year): Dose based on weight, typically 0.5 mg/kg twice daily
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Dose adjustment required in renal impairment
Administration:
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Shake well before use
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Administer orally with or without food
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Use a proper measuring device
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Do not mix with other liquids unless directed
Interaction:
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Reduces absorption of certain drugs requiring acidic pH (e.g., ketoconazole, itraconazole)
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Minimal interaction with antacids
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No major CYP450 interaction
Contraindications:
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Hypersensitivity to Famotidine or other H2 blockers
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Not recommended in severe renal failure without dose adjustment
Side Effects:
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Common: Headache, nausea, diarrhea, constipation
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Rare: Drowsiness, rash, confusion (elderly), arrhythmias
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Long-term use: Risk of vitamin B12 deficiency
Pregnancy & Lactation:
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Category B: Safe in pregnancy if clearly needed
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Use with caution during breastfeeding
Precautions & Warnings:
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Rule out malignancy before starting treatment for gastric ulcers
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Monitor renal function in long-term users
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Use cautiously in infants and elderly
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Avoid prolonged unsupervised use
Therapeutic Class:
H2-Receptor Antagonist
Storage Conditions:
Store below 25°C in a dry place. Protect from light. Keep out of reach of children. Do not freeze.
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