Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
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Type 2 Diabetes Mellitus (T2DM) to improve glycemic control
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May be used in combination with other antidiabetic agents
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To reduce risk of cardiovascular death in adults with T2DM and established cardiovascular disease
Pharmacology:
Empagliflozin is a selective sodium-glucose co-transporter 2 (SGLT2) inhibitor. It reduces renal glucose reabsorption and increases urinary glucose excretion, thereby lowering plasma glucose levels.
Dosage:
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Recommended starting dose: 10 mg once daily
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May be increased to 25 mg once daily if additional glycemic control is needed
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Dose adjustment not required for mild renal impairment
Administration:
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Oral administration, preferably in the morning
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Can be taken with or without food
Interaction:
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Diuretics: May enhance the risk of dehydration
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Insulin or insulin secretagogues: Risk of hypoglycemia
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May interact with lithium and increase its toxicity
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Monitor with blood pressure-lowering agents due to volume depletion
Contraindications:
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Hypersensitivity to Empagliflozin
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Severe renal impairment, end-stage renal disease, or dialysis
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Type 1 diabetes mellitus
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History of diabetic ketoacidosis (DKA)
Side Effects:
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Urinary tract infections, genital mycotic infections
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Dehydration, hypotension
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Increased urination, dizziness
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Rare: ketoacidosis, acute kidney injury
Pregnancy & Lactation:
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Not recommended during second and third trimesters
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Avoid during breastfeeding due to potential adverse effects on renal development in infants
Precautions & Warnings:
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Monitor renal function and fluid status
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Caution in elderly patients and those on diuretics
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Educate patient about signs of urinary tract infections or ketoacidosis
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Not recommended for type 1 diabetes or for diabetic ketoacidosis
Therapeutic Class:
SGLT2 Inhibitors (Sodium-glucose cotransporter 2 inhibitors)
Storage Conditions:
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.
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