Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications:
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Treatment of hypertension
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Management of chronic stable angina pectoris
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Treatment of supraventricular tachyarrhythmias including atrial fibrillation and flutter
Pharmacology:
Diltiazem SR is a nondihydropyridine calcium channel blocker that inhibits calcium influx in cardiac and vascular smooth muscles. This causes vasodilation, reduces myocardial oxygen demand, lowers heart rate, and helps control blood pressure.
Dosage:
Typical adult dose: 120 mg once daily. Dose can be adjusted up to 360 mg daily based on clinical response.
Do not crush or chew the sustained-release tablet.
Administration:
Take orally, preferably at the same time each day with or without food. Swallow tablet whole with water.
Interaction:
May interact with:
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Beta-blockers
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Digoxin
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CYP3A4 inhibitors or inducers
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Other antihypertensives
Contraindications:
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Severe hypotension
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Sick sinus syndrome without pacemaker
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Second or third-degree AV block
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Acute myocardial infarction with pulmonary congestion
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Hypersensitivity to Diltiazem
Side Effects:
Common: Headache, dizziness, flushing, peripheral edema, bradycardia, fatigue
Rare: Constipation, rash, nausea, AV block, liver enzyme changes
Pregnancy & Lactation:
Use only if benefit justifies risk. Caution during breastfeeding due to excretion in milk.
Precautions & Warnings:
Regular monitoring of heart rate and blood pressure is recommended. Use cautiously in patients with hepatic or renal impairment and those prone to heart failure.
Therapeutic Class:
Calcium Channel Blockers – Non-dihydropyridine group
Storage Conditions:
Store below 30°C, in a dry place, protected from light and moisture. Keep out of reach of children.
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