Description
• রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
Indications:
METH 2.5 MG is indicated for treatment of cancers like leukemia, lymphoma, autoimmune disorders including rheumatoid arthritis, psoriasis, and severe inflammatory diseases.
Pharmacology:
Methotrexate inhibits dihydrofolate reductase enzyme, preventing folic acid activation needed for DNA and RNA synthesis, thus halting cell division and immune cell proliferation.
Dosage:
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Dosage depends on the condition; typically given weekly in doses ranging from 2.5 mg to 25 mg orally or by injection, as prescribed.
Administration:
Administer orally or by injection as directed by the physician. Monitor blood counts and liver function regularly.
Interaction:
Interacts with NSAIDs, sulfonamides, penicillins, and other drugs affecting renal clearance or folate metabolism, increasing toxicity risk.
Contraindications:
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Hypersensitivity to methotrexate.
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Pregnancy and breastfeeding.
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Severe hepatic or renal impairment.
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Blood dyscrasias.
Side Effects:
May cause nausea, vomiting, mouth ulcers, liver toxicity, bone marrow suppression, pulmonary fibrosis, and infection risk.
Pregnancy & Lactation:
Contraindicated due to teratogenic effects. Use effective contraception and avoid during breastfeeding.
Therapeutic Class:
Antimetabolite; chemotherapy agent; immunosuppressant.
Storage Conditions:
Store in a cool, dry place below 25°C, away from light. Keep out of reach of children.
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