Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
Indications:
CLACIDO 1GM Tablet is indicated for:
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Upper and lower respiratory tract infections (e.g., pharyngitis, sinusitis, bronchitis, pneumonia).
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Skin and soft tissue infections caused by susceptible bacteria.
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Eradication of Helicobacter pylori in combination with other medications for the treatment of duodenal ulcers.
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Mycobacterial infections, including Mycobacterium avium complex (MAC).
Pharmacology:
CLACIDO contains Clarithromycin, a macrolide antibiotic that inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit. This action disrupts bacterial growth and replication, making it effective against a broad spectrum of Gram-positive and Gram-negative bacteria.
Dosage and Administration:
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Dosage:
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Adults: 500 mg to 1 gm daily in divided doses, depending on the severity of the infection.
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Helicobacter pylori Eradication: 500 mg twice daily in combination with a proton pump inhibitor and amoxicillin.
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Administration:
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Swallow the tablet whole with water.
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Can be taken with or without food.
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Interaction:
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Avoid concurrent use with medications like statins (e.g., simvastatin, lovastatin) due to the risk of myopathy.
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Increases the levels of warfarin, digoxin, and certain antiarrhythmics, which may necessitate dose adjustments.
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Avoid use with ergotamine or dihydroergotamine due to the risk of ergot toxicity.
Contraindications:
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Hypersensitivity to Clarithromycin, erythromycin, or other macrolide antibiotics.
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Patients with a history of QT prolongation or ventricular arrhythmias.
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Severe hepatic or renal impairment.
Side Effects:
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Common: Nausea, vomiting, diarrhea, altered taste, and abdominal discomfort.
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Rare: Hepatotoxicity, severe allergic reactions, or cardiac arrhythmias.
Pregnancy & Lactation:
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Pregnancy: Use only if the benefits outweigh the risks, particularly during the first trimester.
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Lactation: Use with caution as Clarithromycin is excreted in breast milk.
Precautions & Warnings:
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Monitor liver and kidney function during prolonged use.
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Use cautiously in patients with existing cardiac conditions or electrolyte imbalances.
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Not recommended for use in children below 12 years without medical advice.
Therapeutic Class:
Macrolide Antibiotic.
Storage Conditions:
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Store below 30°C in a cool, dry place away from direct sunlight.
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Keep out of reach of children.
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