Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন*
Indications:
GLYMIN 850 MG is indicated for the:
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Management of type 2 diabetes mellitus (non-insulin dependent)
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Especially effective in overweight adults where diet and exercise alone are insufficient
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Can be used as monotherapy or with other oral antidiabetic agents or insulin
Pharmacology:
GLYMIN contains Metformin Hydrochloride, a biguanide oral hypoglycemic agent that:
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Inhibits hepatic glucose production
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Delays intestinal absorption of glucose
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Improves insulin sensitivity and peripheral glucose utilization
It does not stimulate insulin secretion, hence has minimal risk of hypoglycemia.
Dosage & Administration:
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Initial dose: 850 mg once daily with a main meal
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May be increased gradually based on blood glucose response
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Maximum recommended dose: 2550 mg/day in divided doses
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Should always be taken with food to minimize GI discomfort
Interaction:
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Alcohol: Increases the risk of lactic acidosis
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Contrast media: Risk of renal impairment and lactic acidosis; discontinue temporarily
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Cimetidine, furosemide, and nifedipine may increase metformin levels
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May interact with insulin or sulfonylureas causing enhanced hypoglycemic effect
Contraindications:
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Renal insufficiency (eGFR < 30 mL/min/1.73 m²)
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Hepatic impairment
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Heart failure or conditions predisposing to hypoxia
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Diabetic ketoacidosis or lactic acidosis
Side Effects:
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Common: Nausea, diarrhea, abdominal bloating, metallic taste
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Rare: Lactic acidosis (life-threatening), vitamin B12 deficiency with long-term use
Pregnancy & Lactation:
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Considered safe under medical supervision during pregnancy
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Can be used with caution during lactation
Precautions & Warnings:
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Monitor renal function before and during therapy
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Discontinue in case of acute illness or dehydration
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Avoid in patients with severe infection, trauma, or surgery
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Stop 48 hours before any contrast-enhanced imaging
Therapeutic Class:
Biguanide – Oral hypoglycemic agent
Storage Conditions:
Store below 30°C in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
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