Description
জিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
Indications:
SERGEL 20 MG Sachet is indicated for:
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Rapid relief from Gastroesophageal Reflux Disease (GERD).
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Treatment of peptic ulcers associated with H. pylori infection or NSAID use.
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Zollinger-Ellison syndrome.
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Erosive esophagitis.
Pharmacology:
Esomeprazole, in granular form in the sachet, is a proton pump inhibitor (PPI) that inhibits gastric acid secretion by blocking the H+/K+ ATPase enzyme in gastric parietal cells. This leads to effective symptom relief and promotes healing of acid-induced lesions.
Dosage and Administration:
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Adults: One sachet (20 mg) daily, or as prescribed by a physician.
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Empty the contents of the sachet into a glass, add 1 tablespoon of water, stir until dissolved, and drink immediately.
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Take at least 1 hour before meals.
Interaction:
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May reduce the absorption of drugs that require an acidic environment (e.g., ketoconazole, atazanavir).
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Use with caution in patients taking warfarin, as it may increase bleeding risks.
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Can reduce the effectiveness of clopidogrel when used concurrently.
Contraindications:
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Hypersensitivity to esomeprazole, other PPIs, or any component of the formulation.
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Severe liver impairment without dose adjustments.
Side Effects:
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Common: Nausea, headache, abdominal pain, diarrhea, flatulence.
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Rare but serious: Severe allergic reactions, hypomagnesemia, and increased fracture risk with prolonged use.
Pregnancy & Lactation:
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Pregnancy: Safe under medical supervision (FDA Category B).
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Lactation: Use with caution; esomeprazole may pass into breast milk.
Precautions & Warnings:
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Prolonged use may lead to vitamin B12 deficiency or increase the risk of bone fractures.
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Monitor magnesium levels during long-term therapy.
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Discontinue use and consult a physician if severe allergic reactions occur.
Therapeutic Class:
Proton Pump Inhibitor (PPI)
Storage Conditions:
Store below 30°C in a dry place away from moisture and light. Keep out of reach of children.
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