Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
Indications:
ROZITH 250 MG Tablet is indicated for:
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Upper and lower respiratory tract infections, including pharyngitis, tonsillitis, bronchitis, and pneumonia.
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Skin and soft tissue infections.
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ENT infections, such as sinusitis and otitis media.
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Some gastrointestinal and urogenital infections caused by susceptible bacteria.
Pharmacology:
Azithromycin is a macrolide antibiotic that binds to the 50S ribosomal subunit of bacteria, inhibiting protein synthesis and preventing bacterial growth. It is effective against a broad range of Gram-positive and Gram-negative bacteria.
Dosage and Administration:
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Adults and Adolescents:
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500 mg on the first day, followed by 250 mg once daily for the next 4 days.
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Can be taken with or without food. Take the tablet with water and avoid splitting or crushing it.
Interaction:
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May interact with antacids containing aluminum or magnesium, reducing azithromycin absorption.
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Concomitant use with ergot derivatives increases the risk of ergot toxicity.
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Can potentiate the effects of anticoagulants like warfarin.
Contraindications:
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Hypersensitivity to azithromycin, erythromycin, or other macrolide antibiotics.
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Severe hepatic impairment or jaundice caused by previous azithromycin use.
Side Effects:
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Common: Nausea, diarrhea, abdominal pain, vomiting, and headache.
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Rare but serious: QT prolongation, allergic reactions, hepatotoxicity.
Pregnancy & Lactation:
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Pregnancy: Use only if the potential benefit justifies the potential risk to the fetus.
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Lactation: Use with caution as azithromycin may pass into breast milk.
Precautions & Warnings:
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Use with caution in patients with liver dysfunction or preexisting heart conditions.
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Discontinue immediately if severe allergic reactions or Clostridioides difficile-associated diarrhea occurs.
Therapeutic Class:
Macrolide Antibiotic
Storage Conditions:
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
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