Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন*
Indications:
NEOPENEM 500 MG is indicated for treating infections caused by susceptible bacteria, such as:
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Intra-abdominal infections
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Community and hospital-acquired pneumonia
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Urinary tract infections (including pyelonephritis)
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Skin and soft tissue infections
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Septicemia
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Meningitis
Pharmacology:
Meropenem is a carbapenem-class beta-lactam antibiotic. It works by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins, resulting in bacterial cell death. It is effective against a wide range of Gram-positive, Gram-negative, and anaerobic bacteria.
Dosage & Administration:
Adults:
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500 mg every 8 hours IV for most infections.
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Severe infections: dosage may be increased up to 1 g every 8 hours.
Infuse over 15–30 minutes. Dosage must be adjusted in patients with renal impairment.
Interaction:
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Probenecid may increase Meropenem levels.
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May reduce plasma concentration of valproic acid.
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Use with caution with other nephrotoxic drugs.
Contraindications:
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Known hypersensitivity to Meropenem or other carbapenem antibiotics.
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History of severe allergic reactions to beta-lactams (e.g., penicillins, cephalosporins).
Side Effects:
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Common: Diarrhea, nausea, rash, headache, injection site inflammation.
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Serious: Seizures (especially in renal dysfunction), hypersensitivity reactions, antibiotic-associated colitis.
Pregnancy & Lactation:
Use only if clearly needed and prescribed during pregnancy. Caution advised during breastfeeding as Meropenem may pass into breast milk.
Precautions & Warnings:
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Monitor renal function, especially in elderly or renally impaired patients.
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Prolonged use may lead to secondary infections or resistant organisms.
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Monitor for hypersensitivity reactions.
Therapeutic Class:
Carbapenem antibiotic – Injectable
Storage Conditions:
Store below 25°C, in a dry place, protected from light. Reconstituted solution should be used promptly or as directed on the packaging. Keep out of reach of children.
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