Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন*
Indications:
EVANIA 10 MG is indicated for:
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Management of hypertension (high blood pressure)
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Treatment of chronic stable angina
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Vasospastic (Prinzmetal’s) angina
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Prevention of cardiovascular events in at-risk patients
Pharmacology:
EVANIA contains Amlodipine Besylate, a long-acting dihydropyridine calcium channel blocker. It inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle, resulting in vasodilation and reduced blood pressure. It also decreases myocardial oxygen demand by reducing afterload.
Dosage & Administration:
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Adults: 5–10 mg once daily; usual dose is 5 mg, may be increased to 10 mg based on patient response.
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Elderly or hepatic impairment: Start at the lower dose (5 mg).
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Can be taken with or without food.
Interaction:
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Potentiation of antihypertensive effect with other BP-lowering agents (e.g., ACE inhibitors, diuretics)
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Caution with CYP3A4 inhibitors (e.g., ketoconazole, erythromycin) – may increase amlodipine levels
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May increase exposure to simvastatin
Contraindications:
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Known hypersensitivity to amlodipine
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Severe hypotension
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Cardiogenic shock
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Aortic stenosis (severe)
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Unstable angina (during dose titration)
Side Effects:
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Common: Edema (especially ankle), dizziness, headache, flushing, fatigue
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Less common: Palpitations, nausea, abdominal pain
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Rare: Hepatic dysfunction, allergic reactions, gingival hyperplasia
Pregnancy & Lactation:
Use only if clearly needed during pregnancy. Not recommended during lactation unless prescribed by a physician.
Precautions & Warnings:
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Caution in patients with hepatic impairment, heart failure, or severe aortic stenosis
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Monitor blood pressure regularly
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Gradual dose adjustment is advised to avoid hypotension
Therapeutic Class:
Calcium Channel Blockers (Dihydropyridine group)
Storage Conditions:
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
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