রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন*
Indications:
Treatment of essential hypertension
Management of type 2 diabetes mellitus
Suitable for patients requiring combined antihypertensive and antidiabetic therapy
Pharmacology:
This combination contains:
Isradipine: A calcium channel blocker that dilates blood vessels, reducing blood pressure and cardiac workload.
Metformin: An oral antidiabetic agent that decreases hepatic glucose production and improves peripheral insulin sensitivity, lowering blood glucose.
Dosage & Administration:
Dose individualized by healthcare professional
Usually taken once daily with meals to reduce gastrointestinal side effects
Swallow whole; do not crush or chew
Interaction:
May enhance effects of other antihypertensive agents
Metformin interacts with agents affecting renal function and iodinated contrast media
Avoid alcohol to reduce risk of lactic acidosis
Regular monitoring of blood glucose and renal function advised
Contraindications:
Hypersensitivity to Isradipine, Metformin, or excipients
Severe renal or hepatic impairment
Metabolic acidosis or diabetic ketoacidosis
Pregnancy and lactation unless benefits outweigh risks
Side Effects:
Common: Dizziness, headache, flushing, nausea, diarrhea
Less common: Edema, fatigue, hypoglycemia (rare)
Rare: Lactic acidosis, allergic reactions
Pregnancy & Lactation:
Pregnancy: Use only if clearly needed with physician’s advice
Lactation: Metformin is excreted in breast milk; consult healthcare provider
Precautions & Warnings:
Regular blood pressure, blood glucose, and kidney function monitoring necessary
Avoid sudden discontinuation
Use caution in elderly or patients with cardiovascular disease
Report any signs of lactic acidosis or allergic reactions promptly
Therapeutic Class:
Combination of Calcium Channel Blocker and Oral Antidiabetic Agent
Storage Conditions:
Store in a cool, dry place below 25°C
Protect from light and moisture
Keep out of reach of children
Do not use after expiry date