SERGEL 20 MG Capsule

SERGEL 20 MG Capsule

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Product Code : 109310709602702

Short Description

SERGEL 20 MG Capsule contains esomeprazole, a proton pump inhibitor used to treat acid-related disorders like GERD, ulcers, and Zollinger-Ellison syndrome.

Name	Brand	Generic Name	Strength	PPF	Price
SERGEL 20 MG Capsule	Healthcare Pharmaceuticals Ltd.	ESOMEPRAZOLE	20 mg	Capsule	7

৳ 7

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Description

রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।

Indications:
SERGEL 20 MG Capsule is indicated for:

Gastroesophageal Reflux Disease (GERD).
Peptic ulcers associated with H. pylori infection or NSAID use.
Zollinger-Ellison syndrome.
Erosive esophagitis.
Long-term management of acid-related disorders.

Pharmacology:
Esomeprazole is a proton pump inhibitor (PPI) that blocks the hydrogen-potassium ATPase enzyme in the gastric parietal cells. This action reduces gastric acid secretion, providing relief from acid-related symptoms and promoting healing of ulcers and erosions.

Dosage and Administration:

Adults: 20 mg once daily, at least 1 hour before meals.
Duration of therapy varies based on the condition (e.g., 4-8 weeks for GERD).
Swallow the capsule whole; do not crush or chew.

Interaction:

May reduce the absorption of drugs like ketoconazole and atazanavir that require acidic conditions for absorption.
Concurrent use with warfarin may increase bleeding risk; monitor INR levels.
Omeprazole may interfere with the effectiveness of clopidogrel.

Contraindications:

Hypersensitivity to esomeprazole, other PPIs, or any component of the formulation.
Severe liver impairment without dose adjustment.

Side Effects:

Common: Headache, diarrhea, nausea, flatulence, abdominal pain.
Rare but serious: Vitamin B12 deficiency with prolonged use, bone fracture risk, and severe allergic reactions.

Pregnancy & Lactation:

Pregnancy: Esomeprazole is classified as Category B by the FDA. Safe when prescribed by a doctor.
Lactation: Use with caution as it may pass into breast milk.

Precautions & Warnings:

Prolonged use may increase the risk of Clostridium difficile infection or bone fractures.
Monitor magnesium levels during prolonged therapy.
Discontinue immediately if hypersensitivity reactions occur.

Therapeutic Class:
Proton Pump Inhibitor (PPI)

Storage Conditions:
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.