Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন*
Indications:
OXOFYLINE 100 ML is indicated for:
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Bronchial asthma
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Chronic Obstructive Pulmonary Disease (COPD)
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Chronic bronchitis
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Other obstructive airway diseases
Pharmacology:
Doxofylline is a methylxanthine derivative that acts as a bronchodilator. It inhibits phosphodiesterase enzymes, increasing intracellular cAMP levels, which relax bronchial smooth muscles. Unlike theophylline, it has fewer cardiovascular and gastrointestinal side effects.
Dosage & Administration:
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Adults: 10 ml (containing 400 mg Doxofylline) twice daily or as prescribed
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Children (based on weight and age): Typically lower doses; follow physician's advice
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Best taken after meals
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Shake well before use
Interaction:
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Caution with other xanthines or stimulants
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May potentiate effects of beta-agonists
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Reduced clearance in patients on macrolide antibiotics or fluoroquinolones
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Alcohol may increase toxicity
Contraindications:
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Known hypersensitivity to Doxofylline or related compounds
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Acute myocardial infarction
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Severe hypotension
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Active peptic ulcer
Side Effects:
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Common: Nausea, vomiting, headache, restlessness
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Less common: Palpitations, insomnia, tremor
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Rare: Arrhythmias, seizures (in overdose or renal impairment)
Pregnancy & Lactation:
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Use in pregnancy only if clearly needed; consult a physician
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Unknown whether excreted in breast milk; caution advised during lactation
Precautions & Warnings:
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Avoid use in patients with seizure disorders
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Monitor cardiac patients for arrhythmias
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Use cautiously in hepatic and renal impairment
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Avoid smoking as it reduces efficacy
Therapeutic Class:
Xanthine Derivatives / Bronchodilators
Storage Conditions:
Store below 30°C in a dry place. Protect from light and moisture. Keep out of reach of children. Do not freeze.
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