রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন*
Indications:
NIRVANA 20 MG is indicated for the treatment of:
Major Depressive Disorder (MDD)
Generalized Anxiety Disorder (GAD)
Panic Disorder
Social Anxiety Disorder (off-label use)
Obsessive-Compulsive Disorder (off-label use)
Pharmacology:
Escitalopram is a selective serotonin reuptake inhibitor (SSRI). It enhances serotonergic activity by inhibiting the reuptake of serotonin (5-HT) into the presynaptic neuron. This increase in serotonin levels helps elevate mood and reduce anxiety.
Dosage & Administration:
Usual adult dose: Start with 10 mg once daily, may increase to 20 mg/day after 1 week depending on patient response
Should be taken once daily, at the same time each day
Can be taken with or without food
Dose adjustments may be necessary in elderly patients or those with hepatic impairment
Interaction:
Avoid concomitant use with MAOIs or other serotonergic agents to prevent serotonin syndrome
Increased bleeding risk with NSAIDs, aspirin, or anticoagulants
Alcohol may enhance sedative effects
Caution with drugs that prolong QT interval
Contraindications:
Hypersensitivity to Escitalopram
Concomitant use with MAO inhibitors (within 14 days)
Uncorrected electrolyte disturbances (e.g., hypokalemia, hypomagnesemia) in patients at risk for QT prolongation
Side Effects:
Common: Nausea, insomnia, drowsiness, dizziness, dry mouth
Less common: Weight changes, sexual dysfunction, agitation
Serious: Suicidal ideation, serotonin syndrome, hyponatremia, QT prolongation
Pregnancy & Lactation:
Use during pregnancy only if clearly needed and prescribed
May cause withdrawal symptoms in neonates if taken late in pregnancy
Caution advised during breastfeeding as the drug is excreted in breast milk
Precautions & Warnings:
Monitor closely for worsening depression or suicidal thoughts
Gradual dose reduction is recommended to avoid withdrawal symptoms
Use caution in patients with seizure disorders or liver impairment
May impair judgment—avoid driving or operating machinery initially
Therapeutic Class:
Selective Serotonin Reuptake Inhibitors (SSRIs)
Storage Conditions:
Store below 30°C in a dry place, protected from light and moisture. Keep out of reach of children.