Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন*
Indications:
NEXOVAS 5 MG is indicated for:
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Management of mild to moderate essential hypertension
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Cardiovascular protection in hypertensive patients
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Prevention of target organ damage due to high blood pressure
Pharmacology:
Cilnidipine is a fourth-generation dihydropyridine calcium channel blocker that blocks both L-type and N-type calcium channels. It lowers blood pressure by relaxing vascular smooth muscle and reducing peripheral resistance. Its N-type blocking action also reduces sympathetic nerve activity.
Dosage & Administration:
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Initial dose: 5 mg once daily
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May be adjusted up to 10–20 mg depending on patient response
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Should be taken at the same time each day, with or without food
Interaction:
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Additive hypotensive effects with other antihypertensive agents
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Use cautiously with CYP3A4 inhibitors (e.g., erythromycin, ketoconazole)
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Avoid taking with grapefruit juice
Contraindications:
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Hypersensitivity to Cilnidipine
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Severe aortic stenosis
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Cardiogenic shock
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Acute myocardial infarction
Side Effects:
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Common: Headache, flushing, dizziness, leg swelling
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Less common: Palpitations, fatigue, nausea
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Rare: Allergic reactions, hypotension, bradycardia
Pregnancy & Lactation:
Not recommended during pregnancy unless clearly needed. Caution advised during breastfeeding due to limited safety data.
Precautions & Warnings:
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Monitor blood pressure and heart rate regularly
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Use with caution in patients with liver impairment
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May cause dizziness—avoid driving until effects are known
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Do not discontinue abruptly
Therapeutic Class:
Calcium Channel Blockers – Dihydropyridine group (L/N-type)
Storage Conditions:
Store below 30°C, away from moisture and direct sunlight. Keep out of reach of children.
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