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EVAGLIP 10 MG/5 MG

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Product Code : 109313899800802

Short Description

EVAGLIP 10/5 MG is a combination oral antidiabetic drug used for managing type 2 diabetes mellitus effectively.

Name Brand Generic Name Strength PPF Price
EVAGLIP 10 MG/5 MG Healthcare Pharmaceuticals Ltd. EMPAGLIFLOZIN & LINAGLIPTIN 10 mg/5 mg TABLET 30
৳ 30
Qty :

Description

রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন*

Indications:
EVAGLIP 10 MG/5 MG is indicated for:

  • Treatment of type 2 diabetes mellitus in adults who are not adequately controlled on metformin or vildagliptin alone.

  • As an adjunct to diet and exercise to improve glycemic control.

Pharmacology:
EVAGLIP is a fixed-dose combination of Vildagliptin (50 mg) and Metformin (500/1000 mg).

  • Vildagliptin is a DPP-4 inhibitor that enhances the levels of active incretin hormones, improving insulin secretion and reducing glucagon levels.

  • Metformin decreases hepatic glucose production and improves insulin sensitivity in peripheral tissues.

Dosage & Administration:

  • Typically, one tablet twice daily with meals or as directed by a physician.

  • Dose adjustments may be required based on patient’s renal function and previous therapy.

  • Administer with food to reduce gastrointestinal side effects.

Interaction:

  • Caution with other hypoglycemic agents or insulin (may cause hypoglycemia).

  • Alcohol may potentiate the effect of metformin (lactic acidosis risk).

  • Use caution with diuretics, corticosteroids, and beta-blockers.

Contraindications:

  • Hypersensitivity to vildagliptin, metformin, or any excipients

  • Renal impairment (eGFR < 30 mL/min)

  • Acute or chronic metabolic acidosis (e.g., lactic acidosis)

  • Hepatic dysfunction

Side Effects:

  • Common: Nausea, diarrhea, headache, dizziness

  • Less common: Flatulence, upper respiratory tract infection

  • Rare: Lactic acidosis (from metformin), pancreatitis (from vildagliptin), elevated liver enzymes

Pregnancy & Lactation:
Not recommended during pregnancy unless clearly necessary. Metformin is excreted in breast milk; vildagliptin’s safety in lactation is unknown. Use with caution.

Precautions & Warnings:

  • Monitor renal and liver function regularly

  • Discontinue in case of conditions predisposing to hypoxia or dehydration

  • Watch for signs of lactic acidosis and pancreatitis

  • Avoid alcohol consumption

Therapeutic Class:
Oral Anti-diabetic drugs – DPP-4 inhibitor + Biguanide combination

Storage Conditions:
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.