Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
Indications:
CLONATRIL 1MG Tablet is indicated for:
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Anxiety disorders and panic attacks.
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Seizure disorders, including epilepsy and Lennox-Gastaut syndrome.
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Adjunct therapy for acute manic episodes and agitation.
Pharmacology:
Clonazepam is a benzodiazepine that enhances the effect of gamma-aminobutyric acid (GABA), a neurotransmitter responsible for reducing excessive neural activity. This results in a calming effect on the brain, helping manage anxiety, panic disorders, and seizures effectively.
Dosage and Administration:
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Dosage:
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Adults: 0.5 mg to 1 mg daily, increasing gradually to a maximum of 20 mg/day as needed.
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Children: Dosage is weight-dependent, usually starting at 0.01–0.03 mg/kg/day.
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Administration:
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Take the tablet orally with a glass of water.
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Can be taken with or without food.
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Interaction:
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Avoid combining with alcohol or other central nervous system depressants.
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May interact with medications like phenytoin, carbamazepine, and other drugs metabolized by CYP450 enzymes.
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Potentiates the sedative effects of opioids.
Contraindications:
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Hypersensitivity to Clonazepam or other benzodiazepines.
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Severe respiratory impairment or hepatic dysfunction.
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History of substance abuse or benzodiazepine dependency.
Side Effects:
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Common: Drowsiness, fatigue, dizziness, and reduced coordination.
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Rare: Respiratory depression, dependency with long-term use, or cognitive impairment.
Pregnancy & Lactation:
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Pregnancy: Avoid use unless absolutely necessary, as it may harm the fetus.
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Lactation: Caution is advised as Clonazepam is excreted in breast milk.
Precautions & Warnings:
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Avoid abrupt discontinuation to prevent withdrawal symptoms.
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Use cautiously in patients with respiratory issues or a history of substance dependency.
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Prolonged use may result in tolerance and dependency; short-term use is preferred.
Therapeutic Class:
Benzodiazepine, Anticonvulsant.
Storage Conditions:
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Store below 30°C in a cool, dry place, protected from sunlight.
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Keep out of reach of children.
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