Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন*
Indications:
NEXOVAS 10 MG is indicated for:
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Essential hypertension (high blood pressure)
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Cardiovascular protection in patients at risk
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Adjunct in preventing heart-related complications
Pharmacology:
Cilnidipine is a dihydropyridine calcium channel blocker that blocks both L-type and N-type calcium channels. It helps relax blood vessels, reduce peripheral resistance, and lower blood pressure. It also reduces sympathetic nerve activity, which provides additional cardiovascular protection.
Dosage & Administration:
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Usual adult dose: 5–10 mg once daily, may be increased to 20 mg depending on response.
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Take orally with or without food at a fixed time daily.
Interaction:
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Enhanced hypotensive effect with other antihypertensive drugs.
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Use cautiously with CYP3A4 inhibitors (e.g., ketoconazole) and inducers (e.g., rifampicin).
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Avoid grapefruit juice.
Contraindications:
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Known hypersensitivity to Cilnidipine or other calcium channel blockers
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Severe aortic stenosis
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Cardiogenic shock
Side Effects:
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Common: Headache, dizziness, flushing, ankle swelling
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Less common: Bradycardia, fatigue, gastrointestinal upset
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Rare: Hypotension, palpitations, allergic reactions
Pregnancy & Lactation:
Use only if clearly needed and prescribed by a physician. Safety during lactation is not established; caution is advised.
Precautions & Warnings:
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Monitor blood pressure regularly
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Caution in patients with liver dysfunction or heart failure
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Avoid sudden discontinuation
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May cause dizziness; avoid driving or operating machinery until effects are known
Therapeutic Class:
Calcium Channel Blockers – Dihydropyridine group (L/N-type)
Storage Conditions:
Store below 30°C in a cool, dry place away from sunlight. Keep out of reach of children.
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