Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন*
Indications:
OXOFYLINE 200 MG is indicated for:
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Bronchial asthma
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Chronic Obstructive Pulmonary Disease (COPD)
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Chronic bronchitis
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Other chronic obstructive airway conditions
Pharmacology:
Doxofylline is a xanthine derivative and a bronchodilator. It works by inhibiting phosphodiesterase (PDE) enzymes, especially PDE3 and PDE4, increasing intracellular cAMP. This results in relaxation of bronchial smooth muscles and ease in airflow. Compared to theophylline, it has a lower incidence of adverse effects.
Dosage & Administration:
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Adults: 200–400 mg orally twice daily or as directed by physician
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Best taken after food
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Dosage may vary based on clinical condition, age, liver, and renal function
Interaction:
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May enhance the effect of β2-agonists
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Risk of toxicity increases when combined with other methylxanthines
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Use cautiously with drugs like erythromycin, ciprofloxacin, or cimetidine
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Alcohol increases the risk of side effects
Contraindications:
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Hypersensitivity to Doxofylline or other xanthines
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Acute myocardial infarction
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Hypotension
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Active peptic ulcer disease
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Seizure disorders
Side Effects:
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Common: Nausea, headache, restlessness, gastric irritation
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Less common: Palpitations, dizziness, muscle cramps
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Rare: Cardiac arrhythmia, convulsions (especially in overdose)
Pregnancy & Lactation:
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Should be used during pregnancy only if clearly needed
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Caution advised while breastfeeding; consult physician
Precautions & Warnings:
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Avoid use in patients with epilepsy or seizure history
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Monitor elderly and those with liver/kidney impairment
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Smoking reduces drug effectiveness
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Do not crush or chew extended-release tablets
Therapeutic Class:
Xanthine Derivatives / Bronchodilators
Storage Conditions:
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.
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