Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন*
Indications:
NFT 100 MG is indicated for:
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Treatment of acute uncomplicated urinary tract infections (UTIs)
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Prophylaxis against recurrent UTIs
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Lower urinary tract infections caused by susceptible bacteria
Pharmacology:
Nitrofurantoin is rapidly excreted into the urine where it inhibits bacterial enzymes involved in carbohydrate metabolism and cell wall synthesis. It is bactericidal in urine and works best in acidic urine.
Dosage & Administration:
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Adults: 100 mg twice daily for 5–7 days for treatment
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For prophylaxis: 50–100 mg once daily at bedtime
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Should be taken with food to enhance absorption and reduce gastrointestinal side effects
Interaction:
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Antacids containing magnesium trisilicate may reduce absorption
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May enhance toxicity of certain drugs like fluconazole
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Reduced efficacy in patients with significantly impaired renal function
Contraindications:
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Hypersensitivity to Nitrofurantoin
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Anuria, oliguria, or significant renal impairment
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History of jaundice or liver disorder due to nitrofurantoin
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Pregnancy at term (38–42 weeks) and neonates under 1 month
Side Effects:
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Common: Nausea, headache, flatulence, urine discoloration (dark yellow/brown)
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Serious: Pulmonary reactions, peripheral neuropathy, hepatotoxicity, hemolytic anemia in G6PD deficiency
Pregnancy & Lactation:
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Generally considered safe in early pregnancy but contraindicated near term
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Small amounts may pass into breast milk—use with caution during breastfeeding
Precautions & Warnings:
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Monitor renal function before and during treatment
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Caution in elderly patients and those with diabetes or electrolyte imbalance
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May cause false-positive urine glucose tests
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Long-term use may cause chronic pulmonary reactions
Therapeutic Class:
Nitrofuran derivatives – Urinary Tract Antibiotics
Storage Conditions:
Store below 25°C in a dry place, away from light and moisture. Keep out of reach of children.
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