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OXOFYLINE 400MG

Availability :
Out Of Stock

Product Code : 109313821600602

Short Description

OXOFYLINE 400 MG (Doxofylline) is a bronchodilator used for asthma and COPD by relaxing airway muscles and easing breathing.

Name Brand Generic Name Strength PPF Price
OXOFYLINE 400MG Healthcare Pharmaceuticals Ltd. DOXOFILLINE 400mg TABLET 10
৳ 10
Qty :

Description

রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন*

Indications:
OXOFYLINE 400 MG is indicated for the treatment and management of:

  • Bronchial asthma

  • Chronic Obstructive Pulmonary Disease (COPD)

  • Chronic bronchitis

  • Other obstructive airway diseases

Pharmacology:
Doxofylline is a xanthine derivative that acts as a bronchodilator. It inhibits phosphodiesterase (PDE) enzymes, leading to increased intracellular cyclic AMP (cAMP), which relaxes bronchial smooth muscles. Doxofylline is better tolerated than theophylline, with fewer adverse effects.

Dosage & Administration:

  • Adults: 400 mg orally twice daily or as directed by a physician

  • Should be taken after meals with water

  • Do not crush or chew the tablet; swallow whole

  • Adjust dose in hepatic or renal impairment as needed

Interaction:

  • May potentiate effects of beta-agonists

  • Risk of toxicity when combined with other xanthine derivatives

  • Interacts with erythromycin, ciprofloxacin, cimetidine (can increase blood levels)

  • Alcohol may enhance CNS side effects

Contraindications:

  • Hypersensitivity to Doxofylline or other methylxanthines

  • Acute myocardial infarction

  • Severe hypotension

  • Active peptic ulcer disease

  • History of seizures

Side Effects:

  • Common: Nausea, vomiting, headache, restlessness

  • Less common: Palpitations, gastric irritation, dizziness

  • Rare: Seizures, cardiac arrhythmias (mainly in overdose)

Pregnancy & Lactation:

  • Use in pregnancy only if clearly needed (consult physician)

  • Not recommended during breastfeeding unless clearly necessary

Precautions & Warnings:

  • Monitor patients with heart disease, epilepsy, liver or kidney dysfunction

  • Avoid in individuals with a history of seizure disorders

  • Smoking reduces the drug’s effectiveness

  • Long-term use requires periodic monitoring of serum levels in special populations

Therapeutic Class:
Xanthine Derivatives / Bronchodilators

Storage Conditions:
Store in a cool, dry place below 30°C. Protect from light and moisture. Keep out of reach of children.