Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
Indications:
SANGRIL 450/50 Tablet is indicated for:
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Medical termination of intrauterine pregnancy up to 49 days of gestation.
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Cervical ripening and induction of labor in specific cases (as prescribed by a physician).
Pharmacology:
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Mifepristone: A synthetic steroid that blocks the action of progesterone, essential for pregnancy maintenance. It induces detachment of the embryo and softens the cervix.
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Misoprostol: A prostaglandin analog that causes uterine contractions to expel the uterine contents.
Dosage and Administration:
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Day 1: One tablet of mifepristone (450 mg) orally.
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Day 2 or 3: One tablet of misoprostol (50 mcg) orally or vaginally, as directed by the physician.
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Follow-up within 14 days to confirm complete termination of pregnancy.
Interaction:
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Avoid concurrent use with corticosteroids due to antagonistic effects on glucocorticoid activity.
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May interact with anticoagulants, increasing bleeding risks.
Contraindications:
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Confirmed or suspected ectopic pregnancy.
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Chronic adrenal failure.
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Hypersensitivity to mifepristone, misoprostol, or any prostaglandins.
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Severe anemia or bleeding disorders.
Side Effects:
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Common: Nausea, vomiting, abdominal cramps, diarrhea, and fatigue.
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Rare but serious: Heavy vaginal bleeding, infection, or incomplete abortion.
Pregnancy & Lactation:
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Pregnancy: Not applicable as it is used for pregnancy termination.
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Lactation: May pass into breast milk; avoid breastfeeding for a few days after administration.
Precautions & Warnings:
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Must be administered under the supervision of a qualified healthcare provider.
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Ensure the patient has access to emergency medical care in case of excessive bleeding or complications.
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Confirm intrauterine pregnancy before administration.
Therapeutic Class:
Antiprogestogen with Prostaglandin Analog
Storage Conditions:
Store below 25°C in a dry place away from light and moisture. Keep out of reach of children
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