Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
Indications:
SERGEL 20 MG Tablet is indicated for:
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Gastroesophageal Reflux Disease (GERD).
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Peptic ulcers caused by H. pylori infection or NSAID use.
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Zollinger-Ellison syndrome.
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Erosive esophagitis.
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Maintenance therapy for acid-related disorders.
Pharmacology:
Esomeprazole, the active ingredient in SERGEL 20 MG Tablet, is a proton pump inhibitor (PPI). It suppresses gastric acid production by inhibiting the H+/K+ ATPase pump in gastric parietal cells, providing relief from acid-related symptoms and promoting healing.
Dosage and Administration:
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Adults: 20 mg once daily, at least 1 hour before meals.
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Course duration depends on the condition (e.g., 4-8 weeks for GERD).
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Swallow the tablet whole with water; do not crush or chew.
Interaction:
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May reduce the absorption of drugs requiring acidic conditions (e.g., ketoconazole, atazanavir).
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May increase bleeding risk when taken with warfarin; monitor INR levels.
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Reduced efficacy of clopidogrel when used concurrently.
Contraindications:
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Known hypersensitivity to esomeprazole, other PPIs, or components of the formulation.
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Severe liver impairment without appropriate dose adjustments.
Side Effects:
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Common: Nausea, headache, diarrhea, flatulence, and abdominal discomfort.
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Rare but serious: Hypomagnesemia, bone fractures with long-term use, and severe allergic reactions.
Pregnancy & Lactation:
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Pregnancy: Considered safe under medical supervision (FDA Category B).
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Lactation: Use with caution, as esomeprazole may pass into breast milk.
Precautions & Warnings:
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Prolonged use may increase risks of bone fractures or vitamin B12 deficiency.
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Monitor magnesium levels if used for an extended period.
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Discontinue use immediately if severe allergic reactions occur.
Therapeutic Class:
Proton Pump Inhibitor (PPI)
Storage Conditions:
Store below 30°C in a cool, dry place away from moisture and light. Keep out of reach of children
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