Description
রেজিস্টার্ড চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন।
DELPARK 2MG Tablet is indicated for:
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Symptomatic treatment of Parkinson’s disease as monotherapy or in combination with levodopa.
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Management of moderate to severe Restless Legs Syndrome (RLS).
Pharmacology
Pramipexole is a dopamine D2/D3 receptor agonist that mimics dopamine's effects by stimulating the receptors directly. It alleviates motor and non-motor symptoms of Parkinson’s disease and reduces sensory and motor disturbances in RLS.
Dosage & Administration
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Parkinson’s Disease:
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Starting dose: 0.125 mg three times daily.
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Gradually increase every 5-7 days to a maximum of 4.5 mg/day in divided doses.
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Maintenance dose varies based on clinical response.
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Restless Legs Syndrome (RLS):
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Start with 0.125 mg once daily, taken 2-3 hours before bedtime.
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Dose adjustments depend on symptom severity, not exceeding 0.5 mg/day.
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Administration: Take orally, with or without food, as directed by a physician.
Interaction
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Drug Interactions:
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Enhanced sedation with CNS depressants or alcohol.
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May interact with dopamine antagonists like antipsychotics, reducing efficacy.
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Food Interactions: Taking with food can minimize gastrointestinal side effects.
Contraindications
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Known hypersensitivity to Pramipexole or any inactive ingredient in the formulation.
Side Effects
Common side effects:
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Nausea, dizziness.
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Sleep disturbances, fatigue.
Rare or severe side effects:
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Hallucinations, compulsive behaviors.
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Hypotension, somnolence.
Pregnancy & Lactation
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Pregnancy: Pramipexole falls under Category C; use only if benefits outweigh potential risks.
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Lactation: Not recommended as it may inhibit prolactin secretion, affecting milk production.
Precautions & Warnings
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Monitor for sudden onset of sleep or drowsiness during daily activities.
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Caution in patients with a history of psychiatric or impulse control disorders.
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Gradual dose reduction is necessary to avoid withdrawal symptoms when discontinuing.
Therapeutic Class
Dopamine agonist for Parkinson’s disease and RLS.
Storage Conditions
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Store in a cool, dry place below 25°C.
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Protect from light and moisture.
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Keep out of reach of children.
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